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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G/A

Under the Securities Exchange Act of 1934
(Amendment No. 1)*

MANHATTAN PHARMACEUTICALS, INC.
(Name of Issuer)
COMMON STOCK, par value $.001 per share
(Title of Class of Securities)
563 118 207
(CUSIP Number)
December 31, 2004
(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

	|   |	Rule 13d-1(b)
	|X|	Rule 13d-1(c)
	|   |	Rule 13d-1(d)

*	The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

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CUSIP No.  563 118 207		Page 2 of 16 Pages

1	NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Atlas Equity I, Ltd.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)			(a)   [  ] (b)   [  ]
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands
NUMBER OF    SHARES    BENEFICIALLY    OWNED BY    EACH    REPORTING    PERSON    WITH		5   6   7   8	SOLE VOTING POWER 1,818,182 SHARED VOTING POWER None SOLE DISPOSITIVE POWER 1,818,182 SHARED DISPOSITIVE POWER None
9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,818,182
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) Not Applicable			[  ]
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 6.6%
12	TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) CO

*SEE INSTRUCTIONS BEFORE FILLING OUT

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CUSIP No.  563 118 207		Page 3 of 16 Pages

1	NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Atlas Master Fund, Ltd.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)			(a)   [  ] (b)   [  ]
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands
NUMBER OF    SHARES    BENEFICIALLY    OWNED BY    EACH    REPORTING    PERSON    WITH		5   6   7   8	SOLE VOTING POWER 1,818,182 SHARED VOTING POWER None SOLE DISPOSITIVE POWER 1,818,182 SHARED DISPOSITIVE POWER None
9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,818,182
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) Not Applicable			[  ]
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 6.6%
12	TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) OO

*SEE INSTRUCTIONS BEFORE FILLING OUT

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CUSIP No.  563 118 207		Page 4 of 16 Pages

1	NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Atlas Global, LLC
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)			(a)   [  ] (b)   [  ]
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION Delaware
NUMBER OF    SHARES    BENEFICIALLY    OWNED BY    EACH    REPORTING    PERSON    WITH		5   6   7   8	SOLE VOTING POWER None SHARED VOTING POWER 1,818,182 SOLE DISPOSITIVE POWER None SHARED DISPOSITIVE POWER 1,818,182
9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,818,182
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) Not Applicable			[  ]
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 6.6%
12	TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) OO

*SEE INSTRUCTIONS BEFORE FILLING OUT

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CUSIP No.  563 118 207		Page 5 of 16 Pages

1	NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Atlas Global Investments, Ltd.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)			(a)   [  ] (b)   [  ]
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands
NUMBER OF    SHARES    BENEFICIALLY    OWNED BY    EACH    REPORTING    PERSON    WITH		5   6   7   8	SOLE VOTING POWER None SHARED VOTING POWER 1,818,182 SOLE DISPOSITIVE POWER None SHARED DISPOSITIVE POWER 1,818,182
9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,818,182
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) Not Applicable			[  ]
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 6.6%
12	TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) CO

*SEE INSTRUCTIONS BEFORE FILLING OUT

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CUSIP No.  563 118 207		Page 6 of 16 Pages

1	NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Atlas Global Investments II, Ltd.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)			(a)   [  ] (b)   [  ]
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands
NUMBER OF    SHARES    BENEFICIALLY    OWNED BY    EACH    REPORTING    PERSON    WITH		5   6   7   8	SOLE VOTING POWER None SHARED VOTING POWER 1,818,182 SOLE DISPOSITIVE POWER None SHARED DISPOSITIVE POWER 1,818,182
9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,818,182
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) Not Applicable			[  ]
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 6.6%
12	TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) CO

*SEE INSTRUCTIONS BEFORE FILLING OUT

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CUSIP No.  563 118 207		Page 7 of 16 Pages

1	NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Balyasny Asset Management L.P.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)			(a)   [  ] (b)   [  ]
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION Delaware
NUMBER OF    SHARES    BENEFICIALLY    OWNED BY    EACH    REPORTING    PERSON    WITH		5   6   7   8	SOLE VOTING POWER 1,818,182 SHARED VOTING POWER None SOLE DISPOSITIVE POWER 1,818,182 SHARED DISPOSITIVE POWER None
9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,818,182
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) Not Applicable			[  ]
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 6.6%
12	TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) OO

*SEE INSTRUCTIONS BEFORE FILLING OUT

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CUSIP No.  563 118 207		Page 8 of 16 Pages

1	NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Dmitry Balyasny
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)			(a)   [  ] (b)   [  ]
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION United States
NUMBER OF    SHARES    BENEFICIALLY    OWNED BY    EACH    REPORTING    PERSON    WITH		5   6   7   8	SOLE VOTING POWER 1,818,182 SHARED VOTING POWER None SOLE DISPOSITIVE POWER 1,818,182 SHARED DISPOSITIVE POWER None
9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,818,182
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 9 EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) Not Applicable			[  ]
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 6.6%
12	TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) IN

*SEE INSTRUCTIONS BEFORE FILLING OUT

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Item 1

(a)

Name of Issuer:

Manhattan Pharmaceuticals, Inc. (the “Company”)

(b)

Address of Issuer’s Principal Executive Offices:

810 Seventh Avenue, 4th Floor New York, NY 10019

Item 2

(a) - (c)

This statement is filed on behalf of the following:

(1)        Atlas Equity I, a Cayman Islands corporation (“AE1”), with its principal business office at c/o SS&C Fund Services N.V., P.O. Box 4671, Pareraweg 45, Curacao, Netherlands Antilles.

(2)        Atlas Master Fund, Ltd., a Cayman Islands corporation (“AMF”), with its principal business office at c/o SS&C Fund Services N.V., P.O. Box 4671, Pareraweg 45, Curacao, Netherlands Antilles. AMF owns 100% of the equity interests in each of AE1, AE2 and AE3.

(3)        Atlas Global, LLC, a Delaware limited liability company (“AG”), with its principal business office at 181 West Madison, Suite 3600, Chicago, IL 60602. AG owns 39.6% of the equity interests in AMF.

(4)        Atlas Global Investments, Ltd., a Cayman Islands corporation (“AGI1”), with its principal business office at c/o SS&C Fund Services N.V., P.O. Box 4671, Pareraweg 45, Curacao, Netherlands Antilles. AGI owns 24.4% of the equity interests in AMF.

(5)        Atlas Global Investments II, Ltd., a Cayman Islands corporation (“AGI2”), with its principal business office at c/o SS&C Fund Services N.V., P.O. Box 4671, Pareraweg 45, Curacao, Netherlands Antilles. AGI2 owns 35.2% of the equity interests in AMF..

(6)        Balyasny Asset Management L.P., a Delaware limited partnership (“BAM”), with its principal business office at 181 West Madison, Suite 3600, Chicago, IL 60602. BAM is the sole managing member of AG and is the investment manager to each of AE1, AE2, AE3, AG, AGI1 and AGI2.

(7)        Dmitry Balyasny, a United States citizen whose business address is 181 West Madison, Suite 3600, Chicago, IL 60602. Dmitry Balyasny is the sole managing member of BAM.

Page 9 of 16 Pages

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(d)

Title of Class of Securities:

Common Stock, par value $.001 per share

(e)

CUSIP Number:

563 118 207

Item 3

If this statement is filed pursuant to Rule 13d-1(b), or 13d-2(b) or (c), check whether the person filing is a:

Not Applicable.

Item 4

Ownership:

AE1

(a)

Amount Beneficially Owned:

1,818,182 shares

(b)

Percent of Class:

6.6%

(c)

Number of Shares as to which person has:

(i)

sole power to vote or to direct vote:

1,818,182 shares

(ii)

shared power to vote or to direct vote:

none

(iii)

sole power to dispose or direct disposition of:

1,818,182 shares

(iv)

shared power to dispose or to direct disposition of:

none

Page 10 of 16 Pages

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AMF

(a)

Amount Beneficially Owned:

By virtue of its ownership of 100% of the equity interest in AE1, AMF may be deemed to beneficially own a total of 1,818,182 shares of the Company’s Common Stock beneficially owned by AE1.

(b)

Percent of Class:

6.6%

(c)

Number of Shares as to which person has:

(i)

sole power to vote or to direct vote:

1,818,182 shares

(ii)

shared power to vote or to direct vote:

none

(iii)

sole power to dispose or direct disposition of:

1,818,182 shares

(iv)

shared power to dispose or to direct disposition of:

none

AG

(a)

Amount Beneficially Owned:

By virtue of its ownership of 39.6% of the equity interest in AMF, AG may be deemed to beneficially own the 1,818,182 shares of the Company’s Common Stock beneficially owned by AMF.

(b)

Percent of Class:

6.6%

Page 11 of 16 Pages

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(c)

Number of Shares as to which person has:

(i)

sole power to vote or to direct vote:

none

(ii)

shared power to vote or to direct vote:

1,818,182 shares

(iii)

sole power to dispose or direct disposition of:

none

(iv)

shared power to dispose or to direct disposition of:

1,818,182 shares

AGI1

(a)

Amount Beneficially Owned:

By virtue of its ownership of 24.4% of the equity interest in AMF, AGI1 may be deemed to beneficially own the 1,818,182 shares of the Company’s Common Stock beneficially owned by AMF.

(b)

Percent of Class:

6.6%

(c)

Number of Shares as to which person has:

(i)

sole power to vote or to direct vote:

none

(ii)

shared power to vote or to direct vote:

1,818,182 shares

(iii)

sole power to dispose or direct disposition of:

none

Page 12 of 16 Pages

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(iv)

shared power to dispose or to direct disposition of:

1,818,182 shares

AGI2

(a)

Amount Beneficially Owned:

By virtue of its ownership of 35.2% of the equity interest in AMF, AGI2 may be deemed to beneficially own the 1,818,182 shares of the Company’s Common Stock beneficially owned by AMF.

(b)

Percent of Class:

6.6%

(c)

Number of Shares as to which person has:

(i)

sole power to vote or to direct vote:

none

(ii)

shared power to vote or to direct vote:

1,818,182 shares

(iii)

sole power to dispose or direct disposition of:

none

(iv)

shared power to dispose or to direct disposition of:

1,818,182 shares

BAM

(a)

Amount Beneficially Owned:

By virtue of its position as investment manager of each of AE1, AE2, AE3, AG, AGI1 and AGI2 and its role as sole managing member of AG, BAM may be deemed to beneficially own the 1,818,182 shares of the Company’s Common Stock beneficially owned by AG, AGI1 and AGI2.

Page 13 of 16 Pages

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(b)

Percent of Class:

6.6%

(c)

Number of Shares as to which person has:

(i)

sole power to vote or to direct vote:

1,818,182 shares

(ii)

shared power to vote or to direct vote:

none

(iii)

sole power to dispose or direct disposition of:

1,818,182 shares

(iv)

shared power to dispose or to direct disposition of:

none

Dmitry Balyasny

(a)

Amount Beneficially Owned:

By virtue of his position as the sole managing member of BAM, Mr. Balyasny may be deemed to beneficially own the 1,818,182 shares of the Company’s Common Stock beneficially owned by BAM.

(b)

Percent of Class:

6.6%

(c)

Number of Shares as to which person has:

(i)

sole power to vote or to direct vote:

1,818,182 shares

(ii)

shared power to vote or to direct vote:

none

Page 14 of 16 Pages

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(iii)

sole power to dispose or direct disposition of:

1,818,182 shares

(iv)

shared power to dispose or to direct disposition of:

none

Item 5

Ownership of Five Percent or Less of a Class:

Not Applicable.

Item 6

Ownership of More than Five Percent on Behalf of Another Person:

Not Applicable

Item 7

Identification and Classification of the Subsidiary Which Acquired theSecurity Being Reported by the Parent Holding Company or Control Person:

Not Applicable

Item 8

Identification and Classification of Members of the Group:

Not Applicable

Item 9

Notice of Dissolution of Group:

Not Applicable.

Item 10

Certification:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

Page 15 of 16 Pages

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SIGNATURE

        After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: February 11, 2005.

ATLAS EQUITY I, LTD.	ATLAS GLOBAL INVESTMENTS, LTD.
By:  SS&C Fund Services, N.V.,	By:  SS&C Fund Services, N.V.,
as administrator	as administrator
By:  /s/Peter Ijsseling    /s/Maarten Robberts	By:  /s/Peter Ijsseling    /s/Maarten Robberts
Peter Ijsseling        Maarten Robberts	Peter Ijsseling        Maarten Robberts
ATLAS MASTER FUND, LTD.	ATLAS GLOBAL INVESTMENTS II, LTD.
By:  SS&C Fund Services, N.V.,	By:  SS&C Fund Services, N.V.,
as administrator	as administrator
By:  /s/Peter Ijsseling    /s/Maarten Robberts	By:  /s/Peter Ijsseling    /s/Maarten Robberts
Peter Ijsseling        Maarten Robberts	Peter Ijsseling        Maarten Robberts
ATLAS GLOBAL, LLC	BALYASNY ASSET MANAGEMENT L.P.
By:  /s/ Scott H. Schroeder	By:  /s/ Scott H. Schroeder
Scott H. Schroeder	Scott H. Schroeder
	/s/ Dmitry Balyasny
	Dmitry Balyasny

Page 16 of 16 Pages