Document And Entity Information [Abstract] Document Type Document Annual Report Amendment Flag Document Period End Date Document Transition Report Entity File Number Document Fiscal Year Focus Document Fiscal Period Focus Entity Registrant Name Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, Address Line Two Entity Address, City or Town Entity Address, State or Province Entity Address, Postal Zip Code City Area Code Local Phone Number Title of 12(g) Security Security Exchange Name Entity Central Index Key Current Fiscal Year End Date Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Interactive Data Current 1 Entity Interactive Data Current Entity Filer Category Entity Emerging Growth Company Entity Small Business Entity Shell Company Entity Common Stock, Shares Outstanding Entity Public Float Trading Symbol Statement of Financial Position [Abstract] Assets Current assets: Cash and cash equivalents Total Short-term investment securities Sum of the amounts paid in advance for capitalized costs that will be expensed with Research and development. Prepaid research and development Other current assets Assets, Current Total current assets Restricted cash Leasehold interest, net Equipment, net Operating Lease, Right-of-Use Asset Right of use asset Goodwill Assets [Default Label] Total assets Liabilities and stockholders' equity Current liabilities: Accounts payable and accrued expenses Other Liabilities, Current Other current liabilities Operating Lease, Liability, Current Lease liability - current portion Lease liability current portion Accrued compensation Liabilities, Current Total current liabilities Deferred rent Deferred revenue, net of current portion Long-term Debt, Excluding Current Maturities Long-term debt Long-term debt non-current Operating Lease, Liability, Noncurrent Lease liability - non current Lease liability non-current Long-term liabilities Liabilities Total liabilities Commitments and contingencies. Commitments and contingencies Stockholders' equity: Preferred stock, $0.001 par value per share (10,000,000 shares authorized, none issued and outstanding as of December 31, 2019 and 2018) Common stock, $0.001 par value per share (150,000,000 shares authorized, 109,425,243 and 83,911,855 shares issued, 109,383,934 and 83,870,546 shares outstanding at December 31, 2019 and 2018, respectively) Additional paid-in capital Treasury Stock, Value Treasury stock, at cost, 41,309 shares at December 31, 2019 and 2018 Accumulated deficit Accumulated deficit Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest Balance Balance Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Preferred stock, par value Preferred stock, par value (in dollars per share) Preferred stock, shares authorized Preferred stock, shares issued Preferred stock, shares outstanding Common stock, par value Common stock, par value (in dollars per share) Common stock, shares authorized Common Stock, Shares Authorized Common stock, shares issued Common stock, shares outstanding Treasury stock, shares Treasury Stock, Shares Income Statement [Abstract] License revenue Costs and expenses: Research and development: n/a. Non-cash stock expense associated with in licensing agreements The aggregate compensation expense related to the grants of stock options and restricted stock that is attributable to research and development expenses during the reporting period. Noncash compensation Other research and development Research and Development Expense Total research and development General and administrative: The aggregate compensation expense related to the grants of stock options and restricted stock that is attributable to general and administrative expenses during the reporting period. Non Cash Compensation General and Administrative Expenses Noncash compensation Other general and administrative General and Administrative Expense Total general and administrative Total costs and expenses Total costs and expenses Operating Income (Loss) Operating loss Other (income) expense: Other (income) expense: Interest Expense Interest expense Other Income Other income Nonoperating Income (Expense) Total other (income) expense, net Net loss Net loss Consolidated net loss Basic and diluted net loss per common share (in dollars per share) Basic and diluted net loss per common share Weighted average shares used in computing basic and diluted net loss per common share (in shares) Statement of Stockholders' Equity [Abstract] Statement [Table] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Common Stock [Member] Common Stock [Member] Additional Paid In Capital [Member] Additional Paid-in Capital [Member] Treasury Stock [Member] Treasury Stock [Member] Retained Earnings [Member] Accumulated Deficit [Member] Statement [Line Items] Shares, Outstanding Balance (in shares) Balance (in shares) Represents the value of stock issued during the period due to the exercise of warrants. Issuance of common stock in connection with exercise of warrants Represents the number of shares of stock issued during the period due to the exercise of warrants. Issuance of common stock in connection with exercise of warrants (in shares) Issuance of restricted stock Issuance of restricted stock (in shares) Debt Conversion, Converted Instrument, Amount Warrants issued with debt financing Stock Issued During Period, Shares, Restricted Stock Award, Forfeited Forfeiture of restricted stock (in shares) Issuance of common stock (net of offering costs) Issuance of common stock (net of offering costs) (in shares) Shares issued Stock Issued During Period, Shares, New Issues Refers to issuance of common stock in at market offering, net of offering costs. Issuance Of Common Stock In At Market Offering Net Of Offering Costs Issuance of common stock in At-the-Market offerings (net of offering costs) Refers to issuance of common stock in at market offering, in shares. Issuance Of Common Stock In At Market Offering Net Of Offering Costs, Shares Issuance of common stock in At-the-Market offerings (in shares) Compensation in respect of restricted stock granted to employees, directors and consultants n/a. Stock Issued During Period Value In Licensing Agreements Shares issued in connection with in-licensing agreements n/a. Shares Issued In Connection With In Licensing Agreements Shares issued in connection with in-licensing agreements (in shares) Specific incremental costs directly attributable to a proposed or actual offering of securities. Offering Costs Offering costs Specific incremental costs directly attributable to a At-the-Market offering of securities which are deferred at the end of the reporting period. Offering Costs At Market Offering costs, at market Statement of Cash Flows [Abstract] CASH FLOWS FROM OPERATING ACTIVITIES Adjustments to reconcile consolidated net loss to net cash used in operating activities: Non-cash stock compensation expense Recognized stock based compensation expense The value of shares issued in connection with in-licensing agreement. Shares Issued In Connection With In Licensing Agreement Shares issued in connection with in-licensing agreement Depreciation and amortization Amortization of premium on investment securities Amortization of premium on investment securities Investment Income, Amortization of Discount Amortization of discount on investment securities Amortization of Debt Issuance Costs Amortization of debt issuance costs Amortization of Lease Incentives Amortization of leasehold interest Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Non-cash change in lease liability and right-of-use asset The change in fair value of notes payable during the period. Change In Fair Value Of Notes Payable Change in fair value of notes payable and accrued interest Changes in assets and liabilities: Increase (Decrease) in Other Current Assets Decrease (increase) in other current assets Increase (Decrease) in Accrued Interest Receivable, Net (Increase) decrease in accrued interest receivable Increase (Decrease) in Other Noncurrent Assets Decrease in other assets (Decrease) increase in accounts payable and accrued expenses Increase in other liabilities Decrease in lease liabilities Increase (Decrease) in Interest Payable, Net Increase in interest payable Increase (Decrease) in Other Current Liabilities Increase in other liabilities Increase in deferred rent Increase in deferred rent Decrease in deferred revenue Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net cash used in operating activities CASH FLOWS FROM INVESTING ACTIVITIES The cash inflow associated with the maturities of held-to-maturity securities. Proceeds from maturity of short-term securities Amount of cash outflow (inflow) through acquisition (sale) of short-term held-to-maturity securities. Payments To Acquire Held To Maturity Securities Short Term Investment in held-to-maturity securities Payments to Acquire Property, Plant, and Equipment Purchases of equipment Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net cash (used in) provided by investing activities CASH FLOWS FROM FINANCING ACTIVITIES Represents the net proceeds from issuance of common stock over-allotments during the period. Proceeds from sale of common stock, net Proceeds from Other Debt Proceeds from debt financings Proceeds from the exercise of warrants Payments of Financing Costs Financing costs paid Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net cash provided by financing activities Cash and Cash Equivalents, Period Increase (Decrease) NET INCREASE (DECREASE) IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH Total cash, cash equivalents and restricted cash CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT END OF YEAR CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT BEGINNING OF YEAR Reconciliation to amounts on consolidated balance sheets: NONCASH TRANSACTIONS Amount of Accrued Financing Costs. Accrued Financing Costs Deferred financing costs Amount of Warrants Issued With Debt Financing. Warrants Issued With Debt Financing Warrants issued with debt financing Amount of Shares Issued In Connection With In Licensing Agreements Value Shares Issued In Connection With In Licensing Agreements Value Shares issued in connection with in-licensing Amount of noncash expense included in APIC to obtain financing associated with the related debt instruments. Reclassification of deferred financing costs to additional paid-in capital ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES. Organization Consolidation And Presentation Of Financial Statements Disclosure And Significant Accounting Policies [Text Block] ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES CASH. AND CASH EQUIVALENTS. Cash And Cash Equivalents Disclosure [Text Block] CASH AND CASH EQUIVALENTS INVESTMENT SECURITIES Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] INVESTMENT SECURITIES FAIR VALUE MEASUREMENTS Fair Value Disclosures [Text Block] FAIR VALUE MEASUREMENTS STOCKHOLDERS' EQUITY Shareholders' Equity and Share-based Payments [Text Block] STOCKHOLDERS' EQUITY OTHER LIABILITIES Other Liabilities Disclosure [Text Block] OTHER LIABILITIES LONG-TERM DEBT. Long-term Debt [Text Block] LONG-TERM DEBT LEASES Lessee, Operating Leases [Text Block] LEASES INCOME. TAXES. Income Tax Disclosure [Text Block] INCOME TAXES License Agreement [Abstract] LICENSE AGREEMENTS The entire disclosure for research, development, and License Agreement activities, including contracts and arrangements to be performed for others and with federal government. License Agreement Disclosure [Text Block] LICENSE AGREEMENTS RELATED PARTY TRANSACTIONS Related Party Transactions Disclosure [Text Block] RELATED PARTY TRANSACTIONS COMMITMENTS AND CONTINGENCIES Commitments and Contingencies Disclosure [Text Block] COMMITMENTS AND CONTINGENCIES QUARTERLY FINANCIAL INFORMATION Quarterly Financial Information [Text Block] QUARTERLY FINANCIAL INFORMATION Reflects the description of business of the entity. Description of Business Disclosure of accounting policy for reporting when there is a substantial doubt about an entity's ability to continue as a going concern for a reasonable period of time (generally a year from the balance sheet date). Disclose: (a) pertinent conditions and events giving rise to the assessment of substantial doubt about the entity's ability to continue as a going concern for a reasonable period of time, (b) the possible effects of such conditions and events, (c) management's evaluation of the significance of those conditions and events and any mitigating factors, (d) possible discontinuance of operations, (e) management's plans (including relevant prospective financial information), and (f) information about the recoverability or classification of recorded asset amounts or the amounts or classification of liabilities. If management's plans alleviate the substantial doubt about the entity's ability to continue as a going concern, disclosure of the principal conditions and events that initially raised the substa Liquidity and Capital Resources Recently Issued Accounting Standards Use of Estimates